The first annotation of the sixth book of the Bibliotheca Sancta — the very first matter Sixtus judged worth marking in the interpreters of the New Testament — is not a disputed reading or a heresy, but a claim of Chrysostom’s about who needs the Scriptures most:

Chrysostom, homily 2 on Matthew — in which he expounds the beginning of this Gospel — not far from the end asserts that the reading and study of divine Scripture pertains more to secular [laypeople] than to monks, and is more necessary to the former than to the latter.

The monk in his cell, the reasoning runs, has his walls; the layman in the world stands under fire, and it is the soldier under fire who most needs his weapons. Whether that claim can stand unqualified — and what the Church’s discipline made of it — Sixtus weighs at length in Annotation 152, Whether anyone can attain salvation without the reading of the Divine Scriptures.

Read the annotation itself: Annotation I, Sacred reading.